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Compared to mice with normal Gls1 expression, Gls1-deficient mice exhibited a significant increase in overall survival after radiotherapy, and their levels of natural killer cells and interferon alpha/gamma proteins were significantly higher than those of mice with normal Gls1 expression

It is unknown whether the IGF-1 LR3 side effects can lead to the development of growth hormone deficiency or long-term health problems such as cardiovascular disease

Samra B, Kantarjian H, Sasaki K, Short N, Khouri R, Khoury J, Champlin R, Kebriaei P, Cortes JE, Jorgensen J, Wang SA, Garcia-Manero G, Kadia T, Borthakur G , Verstovsek S, Daver N, Montalban-Bravo G, Jain N, Konopleva M, Yilmaz M, Naqvi K, O'Brien S, Ravandi F, Jabbour E

PMID: 7952484