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Description

and R.D.A

al., Int

For laboratory research use only.) Selective NNMT inhibitor with documented IC values in preclinical biochemical assays (pmc.ncbi.nlm.nih.gov) Studied in diet-induced obese (DIO) mouse models for effects on adipose tissue and metabolic markers

Although these studies primarily focus on safety and tolerability, they also provide the first human data on pharmacokinetics and, early pharmacodynamic (biomarker)effects