We then discuss evidence that highly reactive free radical species, especially reactive oxygen species (ROS) generated in endometriosis patients damage intracellular structures and genomic material to adversely impact the structural integrity and viability of oocytes, sperm, and embryos, evaluate literature data that implicates oocyte and fetal aneuploidy as contributing factors for infertility caused by endometriosis, and we discuss therapeutic horizons for treatment of endometriosis patients with antioxidant therapies
Through LLPS, stress granule aggregation interrupts translation and sequesters untranslated mRNAs, as demonstrated by super-resolution microscopy, thereby prioritizing stress-responsive mRNA translation (Yan et al., 2025)
Furthermore, these extracellular, normally nuclear proteins impair erythrocyte deformability and increase the adhesive properties of the cells
Infection-mediated early-onset periodontal disease in P/E-selectin-deficient mice