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Description

Metformin prolongs the postprandial fall in plasma ghrelin concentrations in type 2 diabetes

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The results showed significant reductions in fat, such as a 3.7 cm decrease in the upper belly and a 1.9 cm reduction in the thighs, with facial treatments showing particularly good results (3)

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Furthermore, microinjections of leptin in rodents, into the ventromedial hypothalamus (VMH) 21 and the arcuate nucleus (ARC) 22 can decrease food intake massively, suggesting that leptins actions are mediated mainly by the hypothalamus

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