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When activated, Nrf2 disassociates from its repressor protein KEAP1 that reacts with oxidative radicals, translocates to the nucleus, binds to antioxidant response element and induces the transcription of defensive genes

100 mg Phosphatidylcholine (from purified sunflower seed lecithin)

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Damaged hepatocytes may release massive amounts of cell contents, such as nuclear DNA fragments, mitochondrial DNA, high mobility group box-1 (HMGB1), and ATP