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PMID 12909715

So vitamin E is the most important non-enzymatic antioxidant in the skin (23)

Varicose veins develop when venous valves fail and vein walls lose elasticity due to collagen degradation, chronic inflammation, and impaired endothelial function

2.7 Essential oil (EO) extraction Fresh herbs were used to make four replicas for each treatment, 100 g of each replicate were hydro-distilled (HD) for three hours using Clevenger-style equipment [20]