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Whether pharmacological TREK-1 blockade (which is partial and reversible, unlike genetic knockout) carries seizure risk at therapeutic doses is unknown

Ahpra acknowledged that clinicians don't always need separate TGA approval to prescribe unapproved products but doctors must "ensure that treatments are appropriate and that patients understand the additional risks involved"

Pena-Bermudez, Y

And in that study, they actually found that in cancer cells, adding L-carnitine actually, again, supported the, they call it the autophagy flux and helped the mitochondria and actually stimulated mitophagy, which is autophagy specifically happening in the mitochondria