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The active ingredients of the Buyang Huanwu decoction include calycosin-7-O--D-glucoside, 6-hydroxykaempferol-di-O-glucoside, and galloyl-paeoniflorin

doi: 10.1002/14651858.CD006095.pub4 386 MaYYangJYPengXYXiaoKYXuQWangC

When a cell over-expresses NNMT, it does two costly things at once: it burns through methyl-donor capacity, and it diverts nicotinamide away from NAD+ regeneration into an inert metabolite (1-methylnicotinamide) that gets excreted

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