MetS is a complex group of abnormal metabolic symptoms that are closely associated with cardiovascular disease (CVD), including a state comprising abnormal lipid metabolism, hypertriglyceridemia, lowered high-density lipoprotein (HDL) cholesterol, increased arterial blood pressure, and impaired glucose tolerance [4, 5], which progressively causes hypertension, central obesity, insulin resistance (IR), dyslipidemia, and dysregulation of glucose homeostasis, increasing the risk of individuals developing type 2 diabetes mellitus (T2DM) and CVD [6, 7]
In mice, riboflavin-overproducing strains L
Usually cells (including melanocytes) have distinct overlapping mechanisms for coping with ROS/antioxidant imbalance from multiple sources to prevent cellular damage 29,30,31,32,33
Statistical Analysis Data were analyzed using GraphPad Prism 8 (GraphPad Software, San Diego, CA, USA)