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For example, BDNF and its analogues GSB-106 and GSB-214 can upregulate the PI3K/Akt and ERK pathways to promote endogenous neurogenesis after brain injury and improve neurological function ( Conclusion Currently, HIBD remains the leading cause of neonatal death and long-term neurological dysfunction

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Mechanisms leading to gut dysbiosis in COVID-19: current evidence and uncertainties based on adverse outcome pathways