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Key RTKs in eye include VEGF receptors (VEGFR1, VEGFR2, VEGFR3) regulating angiogenesis, FGF receptors (FGFR1-4) controlling cell proliferation and differentiation, EGF receptor family supporting epithelial cell growth, PDGF receptors modulating pericyte recruitment and vessel stabilization

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Patients who feel dramatically better and return to full training too soon before the tissue has actually repaired structurally are at elevated risk of re-injury