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Epigenetic regulation of the thioredoxin-interacting protein (TXNIP) gene by hyperglycemia in kidney

In a study published in the Bulletin of Experimental Biology and Medicine (2003), Epithalon increased telomerase activity by 2.4-fold in human pulmonary fibroblasts and extended the replicative lifespan of these cells beyond the Hayflick limit (passage 44 vs