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Emerging studies using CSF and advanced neuroimaging techniques, such as brain magnetic resonance spectroscopy (MRS) are beginning to uncover neurobiological changes that may further elucidate disease mechanisms

In vitro experiments with SH-SY5Y neuronal cells demonstrated that palmitoyl-L-carnitine treatment enhanced tau phosphorylation, increased mitochondrial fission, and elevated intracellular calcium levels

This gene encodes a receptor protein on the surface of melanocytes which, when activated by the hormone -MSH, triggers the production of melanin

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