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A few practical factors a clinician weighs up: Injection site

Supervised programs allow us to adjust dosing, monitor symptoms, and respond early if something isnt working well for you

While these typically subside within a few days, you should always notify your doctor just in case, Wirtz says

If you have a B-12 deficiency, it can be more challenging to lose weight, and you might feel sluggish or tired, so B-12 injections can help boost your energy and metabolism.