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When hydrolyzing proteins using multiple proteases (either simultaneously or sequentially), the pH and temperature of the reaction should be considered, as they will alter the activity of the protease

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Other NMDA antagonists (i.e., MK801 and memantine) do not have the same anesthetic, analgesic, and antidepressant effects of KET, leaving open the question of its mechanisms of action (Kelland et al., 1993

In the retina, GPER activation can promote the survival of retinal neurons and enhance the function of photoreceptors, which is crucial for maintaining a normal visual capacity [114]