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The researchers reported increased synthesis and mRNA expression of neurogenic differentiation markers including Nestin, GAP43, Tubulin III, and Doublecortin

Cognitive decline and Alzheimers disease Alzheimers disease (AD) is a form of dementia characterized by extracellular deposition of -amyloid plaques, intracellular formation of neurofibrillary tangles, and neuronal loss, eventually leading to brain atrophy and cognitive impairment in affected individuals (57)

Demyelination per se is not only a deficit found in cell function, as it may occur naturally as part of the myelin turnover

doi: 10.1038/s41586-019-1170-y 200 HanJWangCYangHLuoJZhangXZhangXA