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The herbal medicine product should have a history of safe and efficacious use for at least 10 years within the European Union for a well-established use registration

Primarily in the intestines, we house an estimated 38 trillion microbes (Sender et al., 2016), among which at least 2,172 known species (Hugon et al., 2015), comprising about as many (small) microbial cells as we have (large) human ones (Sender et al., 2016)

Effect of SP and L-car on serum hormonal levels following DOX-mediated POI rats To explore hormonal changes in DOX-intoxicated rats and the possible protective role of SP and L-car, the levels of E2, FSH, LH, and AMH were examined in the serum samples ( Fig