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Furthermore, a synergistic effect between smoking and alcohol consumption on elevated ALT levels has been observed in HCV patients, indicating that the combined exposure significantly exacerbates liver injury [84]

Normally highly expressed in the heart, Parkin degrades ACSL4 via ubiquitination, thereby inhibiting the production of PL-PUFAs and suppressing ferroptosis in cardiomyocytes

[PubMed] [Google Scholar] 39.Klicek R, Kolenc D, Suran J, Drmic D, Brcic L, Aralica G, et al