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Transcriptional profiling by RNA sequencing (RNA-seq) of HSCs isolated from 2-year-old Mx1-T3 and Mx1-Cre control mice showed that SIRT3 overexpression increased expression of mitochondrial genes, including Nd4 , Cytb , Nd1 , Cox7a2 , Ndufa6 , Tomm7 , Nd2 and Timm8b (Extended Data Fig
Vit B12 status is also considered as a modulating factor of the phenotypic expression of PD as recent data have intriguingly suggested a potential role of Vit B12 deficiency in motor progression in PD assessed using the Unified Parkinsons Disease Rating Scale (UPDRS) and the ambulatory capacity score and the worsening of cognitive dysfunction evaluated via the mini-mental status examination (MMSE) (Christine et al
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