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The collagen remodeling cycle completes its first full pass, and the cumulative effect of new fiber synthesis becomes visible as improved firmness, reduced sagging in the lower face and neck, and a measurable difference in skin density

Wound Repair and Regeneration, 2015, 23(1): 113

Em especial, porque esse trabalho de desorganizar o biofilme dental (as bactrias e microorganismos) precisa ser feito pela escovao e o creme dental apenas completa o processo