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Thus, a mutation in the TP53 gene could confer protection against ferroptosis in a specific manner

10.1016/0091-7435(81)90004-9 343 WilkinsR

In addition to this, due to the hypoxic environment, the pulmonary blood vessels also constrict, which can lead to an increase in pulmonary blood pressure, and in the long term may result in the formation of HAPE (El Alam et al., 2022)

Rather, they may serve as an additional tool for patients who have reached a weight loss plateau despite adherence to dietary guidelines and physical activity recommendations, or for those experiencing clinically significant weight regain that threatens their metabolic health improvements