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They demonstrated that T cell-derived IFN- activates the JAK/STAT1 pathway, resulting in the formation of STAT1 homodimers that inhibit SLC7A11 transcription ( + T cells, the tumor immune microenvironment (TIME) considerably affects this mechanism, possibly restricting ferroptosis in immunologically inert malignancies ( 4 Ferroptosis and cell death in tumor immunology Ferroptosis represents a unique form of regulated cell death characterized by excessive accumulation of lipid peroxides and reactive oxygen species (ROS)

10.1371/journal.pone.0201540 13 CardeniaV.VivarelliF.CirilloS.PaoliniM.CanistroD.Rodriguez-EstradaM

Overall, L-theanine exhibits plenty of beneficial functions and can be a promising functional additive or supplement in the food and nutritional industry

Dysmetabolic intestinal flora potentially contributes to gout-related metabolic and inflammatory symptoms by promoting Th17 infiltration