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Research has shown that the onset of motor impairments among GBA mutation carriers occurs 1.7-6.0 years sooner than in those without mutations

This creates an extraordinarily high binding affinity with pK = 16.44, approximately 10 million times higher than other tripeptides and comparable to albumins copper binding (pK = 16.2)

Because it influences so many fundamental biological pathways, its introduction into a system that is already compromised can have significant, sometimes catastrophic, consequences

Isolation of human intestinal bacteria capable of producing the bioactive metabolite isourolithin a from ellagic acid