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Overall, the findings demonstrate that GHRP-2 exerts beneficial effects in arthritic rats by promoting weight gain, modulating HPA axis activity, and exerting anti-inflammatory effects, particularly through suppression of IL-6
142 Inflammatory mediators from pyroptosis also impair insulin signaling, increase insulin resistance, and upregulate lipid synthesis genes, contributing to hepatic lipid accumulation
By presenting a forward-looking perspective on therapeutic peptides, we aim to support clinicians in making informed, responsible decisions and engaging in nuanced discussions with patients and colleagues alike
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