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12 weeks (1x daily, 5-on/2-off) 4 vials 60 doses needed (5x12)

Food and Drug Administration (2023) Tirzepatide versus semaglutide once weekly in patients with Type 2 diabetes, The New England Journal of Medicine (2021) Johns Hopkins scientists say risk of pancreatitis doubles for those taking new class of diabetes drugs, John Hopkins Medicine (2013) Normal and disordered gastric emptying in diabetes: Recent insights into (patho)physiology, management and impact on glycaemic control, Diabetologia (2022) GLP-1 receptor agonists and the risk of thyroid cancer, American Diabetes Association (2022) Mounjaro highlights of prescribing information, The U.S

Overall, there is still a lack of convincing evidence for the clinical efficacy of functional food actives, and large-scale, high-quality RCTs are urgently needed to facilitate the translation of these actives from the laboratory to clinical applications

In two recent studies, berberine was shown to outperform metformin, a commonly prescribed drug for PCOS