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Deamidation Deamidation occurs when asparagine (Asn) or glutamine (Gln) residues in the peptide chain lose their amide group and convert to aspartic acid or glutamic acid respectively

A peptide stored at room temperature for a week can lose meaningful potency, and one contaminated with bacteria can cause injection site infection or systemic illness

A complete Certificate of Analysis should show an HPLC result with a single dominant peak at the stated purity, a mass-spectrometry result confirming the molecular weight matches the intended compound, a bacterial endotoxin result from the Limulus Amebocyte Lysate (LAL) assay, the batch or lot number, and the name of an independent testing laboratory with a recent date