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While frank hyperglycemia is uncommon, those with underlying insulin resistance or diabetes should be monitored for any change in glucose control

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Dickkopf (DKK)-1 suppresses prostaglandin endoperoxide synthase (PTGS)-2-induced macrophage and neutrophil recruitment to lung metastases by antagonizing cancer cell non-classical WNT/Planar cell polarity (PCP)-RAC1-JNK signaling, whereas it encourages breast-to-bone metastasis by modulating classical WNT signaling of osteoblasts (99)

Although numerous studies have measured GPX1 activity in patients with sepsis, the results remain inconclusive [32, 33]