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Metformin, commonly used in diabetes management, has been associated with reduced vitamin B12 absorption, potentially through effects on calcium-dependent vitamin B12-intrinsic factor absorption in the terminal ileum

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In recent years, the development of nanoparticle-based vaccines has benefitted from advances in material science that have led to improvements in antigen structure and stability, targeted vaccine delivery, and immunogenicity with good safety profiles

NNMT catalyzes the methylation of nicotinamide (vitamin B3) using S-adenosylmethionine (SAM) as the methyl donor, producing 1-methylnicotinamide (1-MNA) and S-adenosylhomocysteine