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Aptamers have different advantages over antibodies, including much smaller size (making them more appropriate to penetrate solid tumors), less immunogenicity (reducing resistance to treatment), the capability to manipulate their length and physicochemical properties (making them possible to change the half-life, pH sensitivity, flexibility, and conjugation capacity), fast and simple production procedure, negligible inter-batch variation, and better temperature resistance [210,211,212,213,214]

However, BPC-157 is unique

It is not permitted under the current federal guidelines to compound processes because of concerns about potential immunogenicity and an inconsistent purity profile

[26] Individuals with severe liver disease or with a condition called metabolic acidosis are also contraindicated for Lipo-B