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10.1002/ptr.8306 179 ZhuP.JiangW.HeS.ZhangT.LiaoF.LiuD.et al (2021)

446 These inhibitors, such as geldanamycin, bind to the N-terminal nucleotide-binding pocket of HSP90 with higher affinity than ATP, leading to the proteasomal degradation of HSP90-dependent client proteins

o Bone health GH greatly influences bone density and strength

Calibration curves of Glu and GSH were made with standards, and the concentration of GSH was calculated by internal-standard method with 13 C 2 - 15 N-GSH as internal standard, while the concentration of Glu was calculated by external-standard method