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Ultimately, we may find success in treating the rising tide of neurodegenerative disorders by addressing the hidden energetic and metabolic causes beneath the clinical waterline, rather than by focusing exclusively on the visible effects that naturally emerge, in time, above it

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10.1089/ars.2021.0102 234 RamliF

J Pharm Pharmacol 67:2634 Chiang HS, Maric M (2011) Lysosomal thiol reductase negatively regulates autophagy by altering glutathione synthesis and oxidation