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PMID: 29155147): 5-Amino-1MQ showed NNMT selectivity with IC50 of 1.2 microM Reduced body weight and white adipose mass in diet-induced obese mice over 11 days No effect on food intake, suggesting metabolic rather than appetitive mechanism Nicotinamide N-methyltransferase inhibition mimics and boosts exercise-mediated improvements in muscle function in aged mice , published in Scientific Reports (Dimet-Wiley AL et al., 2024

Lung cancer Although some B complex vitamins may help prevent cancer, there is evidence to show that high volumes of vitamin B12 may increase the risk of lung cancer

It primarily helps to boost high-density lipoprotein cholesterol, also known as HDL cholesterol

Research demonstrates reduced adipocyte lipid accumulation and increased basal metabolic rate without feeding-behavior changes