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22 Reduced porin expression significantly limits their uptake, which leads to resistance against these drugs

BPC 157 Peptide Capsules , as a new type of bioactive peptide preparation, have shown broad application prospects in fields such as wound healing, gastrointestinal diseases, and neurological diseases

Signaling proteins directly or indirectly recruited to the phosphorylated docking site include the growth factor receptor-bound protein 2 (Grb2) adaptor, the non-receptor tyrosine kinase Src, Src homology 2 domain-containing (Shc) adaptor protein, the p85 subunit of phosphatidylinositol 3 kinase (PI3K), phospholipase C (PLC), tyrosine phosphatase SHP2, Src homology 2-containing inositol 5-phosphatase 1 (SHIP2), signal transducer and activator of transcription 3 (STAT3) and the multisubstrate docking protein Grb2-associated binding protein (Gab1) [57]

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