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Moreover, in the context of CIPN, supplementation may not be indefinite but of bounded duration in order to alleviate CIPN symptoms

Conversely, when the TKT gene is deleted, specifically in the liver, there is an amelioration of the development of MAFLD in mice fed a high-fat diet

These conditions can include neurodegenerative diseases, i.e., Parkinsons disease or rheumatoid arthritis, cystic fibrosis, and other autoimmune diseases

Furthermore, the study results demonstrate that GSH treatments significantly reduce ROS accumulation in ethanol-treated HepG2 cells and in vivo models, highlighting their potential in mitigating alcohol-induced oxidative stress