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X-linked gene with mosaic expression in females Conversion of 6-phosphogluconolactone to 6-phosphogluconate by lactonase : irreversible Conversion of 6-phosphogluconate to ribulose-5-phosphate by 6-phosphogluconate dehydrogenase : irreversible NADPH produced, CO 2 released Reactions of the Non-Oxidative Phase: Interconversion of ribulose-5-phosphate and xylulose-5-phosphate by phosphopentose epimerase (ribulose-5-phosphate epimerase) : reversible Interconversion of ribulose-5-phosphate and ribose-5-phosphate by phosphopentose isomerase (ribose-5-phosphate ketoisomerase) : reversible Ribose is a major component of nucleic acids

It is difficult to give an exact explanation for these sensations but, like motor nerves, the sensory nerves, along with their connections in the spinal cord and brain, become hyperexcitable during withdrawal

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Curr Med Chem 19:40004005 Gu Y, Dee CM, Shen J (2011) Interaction of free radicals, matrix metalloproteinases and caveolin-1 impacts blood-brain barrier permeability