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These biologically relevant sources of DSBs have diverse end structures, varying from ends that can be directly ligated to more complex end structures that must first be processed by a variety of factors that include polymerases, end-cleaning enzymes, and nucleases (reviewed in ref

Koizumi A, Nozaki J, Ohura T, Kayo T, Wada Y, Nezu J, Ohashi R, Tamai I, Shoji Y, Takada G, Kibira S, Matsuishi T, Tsuji A: Genetic epidemiology of the carnitine transporter OCTN2 gene in a Japanese population and phenotypic characterization in Japanese pedigrees with primary systemic carnitine deficiency

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