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Vitamin B 6 , which encompasses pyridoxine, pyridoxal, pyridoxamine, and their phosphorylated forms, serves as a cofactor in amino acid metabolism, neurotransmitter biosynthesis, and immune regulation 10,15

This severe glutathione deficit was accompanied by elevated ventricular lactate, a clear biomarker indicating that the brains of these patients are relying on highly inefficient, oxygen-deprived anaerobic metabolism due to mitochondrial stress