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A major role of DIO3 is to protect sensitive cells, such as fetal tissue, the placenta and central nervous system, from excessive concentrations of the active hormone, T3 ( Reference Kohrle, Jakob and Contempre 69 , Reference Schomburg 70 )

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As the newest weight-loss drug on the scene, retatrutide targets three receptors: GLP-1, GIP and glucagon