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Solute carrier family 7 member 11 (SLC7A11) is the main active subunit of system Xc-, and it regulates the dynamic GSH level to maintain its equilibrium and thus regulate ferroptosis [7, 68]

The response to EX + SFN was significantly greater than either SFN or EX alone (2.1-fold versus 1.5-fold, p = 0.01)

It leads to infectious mononucleosis and may play a role in the development of Burkitt lymphoma, some nasopharyngeal carcinomas, and a few rare genetic lymphoproliferative disorders

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