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Sementara itu, glutathione adalah jenis antioksidan yang diproduksi secara alami dalam tubuh yang bermanfaat untuk menjaga kesehatan sel-sel kulit

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Under oxidative stress conditions, NRF2 separates from Keap1 and activates the expression of downstream target genes containing antioxidant response elements (ARE), such as iron heavy chain protein (FTH1) and iron light chain protein (FTL), promoting GSH synthesis and regenerating NADPH to exceed ROS production (36, 83)

This limitation has sent researchers on a sprawling quest for better delivery methods