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Indeed, ZF proteins adopt to a wide diversity of folds that differ in the type and arrangement of metal ligands in the primary structure, e.g., CCHH, CCCH and CCHC, respectively, suggesting strongly divergent evolutionary solutions to a common protein folding problem (Figure 3A-D)

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As the vitamin is water-soluble and passed through our kidneys in urine, regular replenishment through natural foods can be difficult to maintain