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For example, a 2022 review noted that in animal studies, BPC 157 reduced hemorrhage, edema, and oxidative damage in models of brain injury all while enhancing neurological recovery

Peripheral patterns of calcitonin-gene-related peptide general somatic sensory innervation: cutaneous and deep terminations

Subcutaneous injection bypasses all of these barriers except plasma half-life, which for unmodified small peptides is generally very short (minutes to low hours, based on class-level pharmacokinetic data for similar unmodified peptides)

At present, DSIP remains an experimental peptide with limited high-quality human data, and it has not been approved as a standard treatment for insomnia or psychiatric conditions