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BPC157 has demonstrated an exceptional safety profile across multiple studies with no evidence of organ toxicity, mutagenicity, or carcinogenicity. Sikiric et al., Journal of Physiology and Pharmacology Long-Term Safety and Human Use Although human clinical trials are limited, the peptide has been used extensively in animal models and self-experimentation circles with no long-term complications reported

High-quality human clinical trials are still lacking, and this peptide is not FDA-approved for any medical use

This was later adapted to the use of OptiPrep and extended to both mouse and rat blood