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10.3390/nu6020466 14 GalliF.BonominiM.BartoliniD.ZatiniL.ReboldiG.MarcantoniniG.et al (2022)

In their research, the flavonolignans in milk thistle proved to be quite capable of absorbing ultraviolet rays, which is one of the two basic mechanisms for protecting the skin against solar radiation.27 Melasmas Melasmas are dark patches on the skin that may result from genetic factors, exposure to ultraviolet radiation, pregnancy, the use of cosmetics, and certain drugs or therapies (e.g., hormone therapy, anti-seizure medications)

You should know that its quite possible to have clinically low vitamin B12 levels without having anemia

showed that adding L-Arginine to labeled asthma medications did not significantly reduce asthma exacerbations