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The phase 3 trial is in 8,000+ patients with established cardiovascular disease and elevated Lp(a) with a hard primary endpoint composite of cardiovascular death, myocardial infarction, stroke, or urgent coronary revascularization requiring hospitalization

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It takes approximately this long for daily dosing to reach a pharmacokinetic equilibrium, where the rate of drug accumulation from daily dosing matches the rate of elimination

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