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It promotes angiogenesis, accelerates wound healing, reduces inflammation, and appears to protect against various forms of GI damage including those caused by NSAIDs, a class of drugs frequently used by lupus patients for joint pain and inflammation

The expression of the Bax, casepase-3, Bcl-2 and Ki-67 in tumor tissues were detected by immunohistochemistry

In this sense, previous in vitro studies performed by our research group have shown that co-administration of conventional chemotherapeutic agents with antioxidants such as melatonin enhances chemotherapeutic-induced cytotoxicity and apoptosis in different cancer cell lines (Uguz et al., 2012