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It is currently in clinical trials as a treatment option for adults with type 2 diabetes (T2DM) and obesity

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Notably, Chac1 expression was significantly downregulated by approximately 95% as early as 3 hours after refeeding, and this suppression persisted for at least 12 hours (Figure 6A)

Molecular mechanism of flucytosine resistance in Candida lusitaniae: contribution of the FCY2, FCY1, and FUR1 genes to 5-fluorouracil and fluconazole cross-resistance