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Previous research has shown that GPx1 is an effective antioxidant enzyme that cannot be replaced by any other selenoprotein to protect against generalized oxidative stress [74,75,76]

The American Journal Of Clinical Nutrition, 77(1), 189-195

They found that the vegetable diet pattern was associated with a lower risk of gestational diabetes while the sweets and seafood diet pattern was correlated with a higher incidence of GDM, concluding that the vegetable diet pattern had a more evident protective effect in women with a familial diabetes (97)

These mediators promote extracellular matrix remodeling, vascular activation, and further immune recruitment, creating a self-sustaining inflammatory niche that facilitates OA progression (Wang B