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Description

Most patients reach their maintenance dose of 1.0 mg by week four, though some may continue escalating to 1.7 mg or 2.4 mg depending on their response and tolerance

Although the CNS is the major issue with ALS, the liver, spleen, and lungs are all impacted

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Acknowledgements: This research was supported by a grant from Ministry of Science, Education and Sports, Republic of Croatia and there is no existing personal conflicts of interest with any of the authors