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In human gingival mesenchymal stem cells, Epitalon regulates gene expression and protein synthesis: it preferentially binds to histones H1/6 and H1/3 at sites that interact with DNA, thus suggesting that binding to histones may be an additional mechanism for enhancing the expression of genes that regulate neuronal differentiation and protein synthesis [10]

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Emerging evidence suggests that tirzepatide may influence systemic inflammatory markers, though there is no FDA indication for anti-inflammatory therapy, and such use would be considered off-label